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Drixenol is the deuteragonist of Osmosis Jones and its spin-off series Ozzy & Drix. He is a by-the-book cold pill who teams up with Osmosis Jones. David Hyde Pierce did his voice in the movie, and Jeff Bennett did his voice in its spin-off TV show. As Mayor Phlegmming convinced Frank, the latter took Drix as a cold pill. He later joined forces with Ozzy to stop Thrax from killing Frank. In the film. he was voiced by David Hyde Pierce who also voiced Slim in A Bug's Life and Dr. Doppler in Treasure Planet. In the TV Series, he was voiced by Jeff Bennett.