Listen to the sound clip Cyclic AMP pathway: Many extracellular signals acting via GPCRs affect the activity of the enzyme adenylyl cyclase and thus alter the intracellular concentration of cyclic AMP. Cyclic AMP exerts most of its effects by activating the enzyme cyclic AMP dependent protein kinase (PKA). Activated PKA then catalyzes the phosphorylation of particular serines or threonines on specific intracellular proteins, thus altering the activity of these target proteins, leading to a cascade of cellular... from Rodrigo Duterte (President) HiFi TTS Computer AI Voice:
Cyclic AMP pathway: Many extracellular signals acting via GPCRs affect the activity of the enzyme adenylyl cyclase and thus alter the intracellular concentration of cyclic AMP. Cyclic AMP exerts most of its effects by activating the enzyme cyclic AMP dependent protein kinase (PKA). Activated PKA then catalyzes the phosphorylation of particular serines or threonines on specific intracellular proteins, thus altering the activity of these target proteins, leading to a cascade of cellular...
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